NATIONAL INSTITUTES OF HEALTH (NIH)
NIAID conducts and supports basic and applied research to better understand, treat, and ultimately prevent infectious, immunologic, and allergic diseases. For more than 60 years, NIAID research has led to new therapies, vaccines, diagnostic tests, and other technologies that have improved the health of millions of people in the United States and around the world.
NIND’s mission is to seek fundamental knowledge about the brain and nervous system and to use that knowledge to reduce the burden of neurological disease for all people.
The National Institute of Mental Health (NIMH) is the lead federal agency for research on mental disorders. Their mission is to transform the understanding and treatment of mental illnesses through basic and clinical research, paving the way for prevention, recovery, and cure.
The mission of NIDA is to advance science on drug use and addiction and to apply that knowledge to improve individual and public health.
The mission of the National Institute on Alcohol Abuse and Alcoholism is to generate and disseminate fundamental knowledge about the effects of alcohol on health and well-being, and apply that knowledge to improve diagnosis, prevention, and treatment of alcohol-related problems, including alcohol use disorder, across the lifespan.
The mission of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is to conduct and support medical research and research training and to disseminate science-based information on diabetes and other endocrine and metabolic diseases; digestive diseases, nutritional disorders, and obesity; and kidney, urologic, and hematologic diseases, to improve people’s health and quality of life.
NICHD was founded in 1962 to investigate human development throughout the entire life process, with a focus on understanding disabilities and important events that occur during pregnancy. NICHD’s mission is to lead research and training to understand human development, improve reproductive health, enhance the lives of children and adolescents, and optimize abilities for all.
The mission of the National Institute of Arthritis and Musculoskeletal and Skin Diseases is to support research into the causes, treatment, and prevention of arthritis and musculoskeletal and skin diseases; the training of basic and clinical scientists to carry out this research; and the dissemination of information on research progress in these diseases.
The mission of the National Institute of Dental and Craniofacial Research (NIDCR) is to advance fundamental knowledge about dental, oral, and craniofacial (DOC) health and disease and translate these findings into prevention, early detection, and treatment strategies that improve overall health for all individuals and communities across the lifespan.
NINR believes that nursing research is the key to unlocking the power and potential of nursing by leveraging nursing’s strengths and unique knowledge and perspectives inherent to the discipline to the benefit of all people.
NHGRI aims to improve the health of all humans through advances in genomics research. As a leading authority in the field of genomics, the mission of the NHGRI is to accelerate scientific and medical breakthroughs that improve human health. We do this by driving cutting-edge research, developing new technologies, and studying the impact of genomics on society.
The National Institute of General Medical Sciences (NIGMS) supports basic research that increases understanding of biological processes and lays the foundation for advances in disease diagnosis, treatment, and prevention.
DEPARTMENT OF DEFENSE
The Medical Research and Development Command supports research and development aimed at protecting the health, readiness and performance of U.S. warfighters. Its portfolio spans battlefield medicine, infectious disease, military operational medicine and other areas where new diagnostics, therapeutics, devices and technologies can address both immediate and long-term military health needs.
The Congressionally Directed Medical Research Programs fund high-impact biomedical research across a broad range of diseases and military health priorities. CDMRP is known for supporting innovative, high-risk and high-gain projects across the full research pipeline, from basic and translational research through clinical studies and technologies intended to improve patient care.
The Defense Threat Reduction Agency supports research and development focused on countering chemical, biological and other weapons-of-mass-destruction threats. Through its Chemical and Biological Technologies programs, DTRA funds fundamental and applied research, medical countermeasures and disruptive technologies designed to protect the warfighter and strengthen national preparedness against emerging threats.
DARPA’s Biological Technologies Office invests in breakthrough research at the intersection of biology, engineering, computing and the physical sciences. Its programs support transformative technologies in areas such as medical countermeasures, diagnostics, tactical care, human performance and recovery, with an emphasis on ambitious concepts that can create new capabilities for national security.
ADDITIONAL FEDERAL FUNDING
Biomedical Advanced Research Development Authority
BARDA supports the advanced development of medical countermeasures that strengthen U.S. preparedness for public health emergencies. Its portfolio spans vaccines, therapeutics, diagnostics and other technologies addressing chemical, biological, radiological and nuclear threats, pandemic influenza and emerging infectious diseases.
National Science Foundation
NSF supports research and innovation across virtually all fields of fundamental science and engineering, with the medical sciences generally outside its core remit. Through competitive grants, it funds discovery-driven and use-inspired research at universities, colleges and other institutions across the United States.
STATE & PRIVATE FUNDING
California Institute for Regenerative Medicine
The California Institute for Regenerative Medicine funds regenerative medicine research across discovery, preclinical, translational and clinical stages, with a strong emphasis on cell and gene therapies. Its programs support academic and industry-led projects designed to move promising science toward clinical development and patient impact.
Cancer Prevention and Research Institute of Texas
The Cancer Prevention and Research Institute of Texas funds cancer research, product development and prevention initiatives across Texas. For life science companies, its Product Development Research program supports promising therapeutics, diagnostics and technologies through early development, including preclinical work, regulatory preparation and clinical studies.
Michael J Fox Foundation
The Michael J. Fox Foundation is a major nonprofit funder of Parkinson’s disease research, supporting programs aimed at accelerating better treatments, disease-modifying therapies and ultimately prevention or cure. Its funding strategy emphasizes translational research, biomarker development and programs that can move promising science toward clinical impact.
Alzheimer’s Drug Discovery Foundation
The Alzheimer’s Drug Discovery Foundation uses a venture-philanthropy model to support drug development, biomarkers and prevention programs for Alzheimer’s disease. It specifically targets promising, higher-risk projects that may be too early for traditional pharmaceutical or federal funding, helping bridge the gap between scientific discovery and commercial development.
National Multiple Sclerosis Society
The National Multiple Sclerosis Society funds basic, translational and clinical research aimed at stopping MS, restoring lost function and ultimately preventing or curing the disease. It has also invested heavily in developing the MS research workforce and supporting collaborative programs that move promising discoveries toward better treatments.
A Breakthrough T1D Venture
The T1D Fund is a venture-philanthropy fund focused on accelerating treatments, prevention and cures for type 1 diabetes through equity investments in T1D-focused companies. It co-invests with venture capital and biopharma partners, supporting early-stage companies developing disease-modifying therapies and potential cures while reinvesting returns back into the mission.
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